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Brief info

Professor Dominic Rowe AM, BSc (Med), MBBS (Hons), PhD is Foundation Professor of Neurology at Macquarie University, Head of Neurology, and Consultant Neurologist at Macquarie University Hospital. MQ Health Neurology is an adult neurology practice that has six neurologists and performs over 8,000 patient episodes per year. MQ Health Neurology manages the integrated care of >175 patients with MND (~10% of all patients in Australia) and  >750 patients with Parkinson’s disease and other movement disorders.

He established the MND Research Centre at Macquarie University in 2013, which is now the largest integrated basic and clinical research unit in Australia (www.mq.edu.au/mnd), together with the Neurodegenerative Disease Biobank at Macquarie University.

Professor Rowe (orcid: 0000-0003-0912-2146) has published 106 manuscripts in peer-reviewed journals, in addition to chapters in textbooks on Motor Neurone Disease, and edited a textbook on the Non Motor Manifestations of Parkinson’s Disease (Oxford University Press). His original manuscripts have attracted over 6300 total citations with >3300 citations over the last five years. His publications in the area of ALS appeared in Nature Genetics (2016, doi: 10.1038/ng.3622., 334 citations, Altmetric score 346 (top 1% of all papers of similar age), Nature Communications (2017, doi: 10.1038/ncomms14774), 87 citations, Altmetric score 243 (top 2%) and  Science Translational Medicine (2018, doi: 10.1126/scitranslmed.aah4066), 197 citations, Altmetric score 537 (top 1%).  Professor Rowe holds two patents in the area of Parkinson’s disease; one that utilizes a blood test in the diagnosis of Parkinson’s disease, and the other that predicts its progression via cytokine genotyping. In addition a patent concerning a blood test in Motor Neuron Disease and other Neurodegenerative diseases was awarded in 2018


Topic: MANAGING MOTOR NEURONE DISEASE

This presentation will seek to cover the challenges of diagnosing and managing Motor Neurone Disease. Areas to be covered will include:

In his practice at Macquarie University Hospital Prof Rowe sees 80 new patients a year with
>150 patients at any one time. Of these, 90 families have been identified as having a genetic cause of their MND.

MND affects >2000 Australians at any one time with slightly more men affected than women. Despite expectations, MND occurs in all age groups (range 19-90) and the average survival from diagnosis to death is 27 months. In 2020 killed 747 Australians (Covid-19 ~ 700 deaths in 2020)

While 10% of MND is genetic, 90% of MND is sporadic (or environmental) and the risk of MND in our society is increasing.